1625 Periwinkle WAY, SANIBEL

This is your opportunity to own a high-visibility commercial lot in the heart of Sanibel. Located along the island’s main thoroughfare in the General Commercial (GC) district, this property offers exceptional exposure and strong traffic counts, making it an ideal site for a restaurant, retail space, or professional office. Formerly home to beloved local favorite Sweet Melissa’s Café, this site presents an exciting opportunity to bring new life to a well-known business location. For buyers with a restaurant vision, there is an option to obtain existing design plans, helping save significant time and expense in the redevelopment process. With frontage along the island’s walking and biking path and constant visibility to both incoming and outgoing traffic, this property delivers outstanding exposure for any business or investment. Centrally positioned in a pedestrian-friendly setting near shops, hotels, and island amenities, it offers an exceptional location for entrepreneurs and investors ready to make their mark on Sanibel’s commercial landscape. Don’t miss this rare opportunity to invest in one of Southwest Florida’s most sought-after island destinations.

224 days on market · Listing updated April 8, 2026

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